本課程授課對象為想從事轉譯醫學研究，或欲充實轉譯醫學知識的臨床醫學研究所學生。過去20年間，隨著系統生物學，以及分子生物學的進步，對於醫學有長足的進展。本所學生多長期從事基礎及臨床醫學工作，進入本所將從臨床服務之外，學習從事醫學研究。本課程的目的，希望使學生獲得最新的轉譯醫學進展新知。
This course designed for the student who intent to pursue translational research during his/her graduate training. The biomedical research has been advanced for the contribution of modern systems biology, and molecular biology in the past two decades. Due to the student in GIBMS devoted in basic and clinical medical researches, the lacking of translational research course design created the need for this course. Therefore, the objective of this course will be providing the most up-to-date knowledge and concept regarding this secanario.
先修科目Prerequisites
無
none
教學方式Teaching Methods
講課
Lecturing
小組討論、腦力激盪(如案例討論、電影欣賞等)
Group discussion, Brain storming, e.g., Case study, Event discussion, Movie review
業師協同教學
Teaching collaborated with industry
評量方式Assessment
期中報告
Midterm report
期末報告
Final report
個人上台報告
Oral Report
成績評量：口頭報告50％、書面報告30％、參與度20％
參考書目Reference
Science Translation Medicine
教學進度Course Schedule
2022/09/13 轉譯醫學的基礎：分子到臨床
Principle of Translational Medicine: Molecules to Medicine
馬文隆(Wen-Lung Ma) 2022/09/20 尋找以及驗證標的
Target identification and validation
馬文隆(Wen-Lung Ma) 2022/09/27 特別演講：癌症疫苗
Special Lecture: Cancer Vaccine
馬文隆(Wen-Lung Ma) 2022/10/04 基因治療
Gene therapy
馬文隆(Wen-Lung Ma) 2022/10/11 討論課
Round Table Discussion
馬文隆(Wen-Lung Ma) 2022/10/18 生物標誌
BioMarker
馬文隆(Wen-Lung Ma) 2022/10/25 生物標誌開發
BioMarker development
馬文隆(Wen-Lung Ma) 2022/11/01 討論課
Round Table Discussion
馬文隆(Wen-Lung Ma) 2022/11/08 早期臨床試驗設計
Early clinical trial design
馬文隆(Wen-Lung Ma) 2022/11/15 模式選擇以及驗證
Model selection and validation
馬文隆(Wen-Lung Ma) 2022/11/22 討論課
Round Table Discussion
馬文隆(Wen-Lung Ma) 2022/11/29 藥理毒性
Pharmaceutical toxicology
馬文隆(Wen-Lung Ma) 2022/12/06 臨床科技轉譯：傳統中醫藥
Translation in clinical technology: Traditional Chinese Medicine
馬文隆(Wen-Lung Ma) 2022/12/13 討論課
Round Table Discussion
馬文隆(Wen-Lung Ma) 2022/12/20 開發性轉譯醫學設計以及分析策略
Design and analysis approaches for discovery translational medicine
馬文隆(Wen-Lung Ma) 2022/12/27 轉譯醫學研究的實驗動物模型
Experimental model for translational research
馬文隆(Wen-Lung Ma) 2023/01/03 討論課
Round Table Discussion
馬文隆(Wen-Lung Ma) 2023/01/10 討論課
Round Table Discussion
馬文隆(Wen-Lung Ma)