課程基本資料
系所 / 年級Department/Grade-Level
生物醫學研究所博士班 1年級
課號 / 班別Course Code
D4D000186 / A
學分數Credits
2 學分
選 / 必修Elective / Required
選修(Elective)
科目中文名稱Course Title (Chinese)
腦瘤中代謝與刺蝟信號(一)
科目英文名稱Course Title (English)
Targeting hedgehog signaling & cancer metabolism in brain tumor (I)
負責教師Instructor
楊哲彥(Yang, Jer-Yen)
開課期間Course Load
一學期
人數上限Enrollment Max.
70 人
已選人數Enrollment Taken
3 人
抽籤自動遞補等候人數Number of the waiting list after ballot
0 人
備註Memo
全英語授課,開放碩士班上修 全英語授課(Full English course)
可選學制 (availability)
大學部
不可選
二技部
不可選
碩士班
不可選
博士班
1年級 至4年級

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教學綱要
課程概述Course Description
The course consists of introducing Hedgehog signaling and cancer metabolism in medulloblastoma and presentation skills training. The course will cover all of the research skills including cancer biology, human and mouse genetic diseases, statistic analysis, AI, deep learning of drug screening, and protein/molecule docking, sharing the research experience in biotech and pharmaceutical companies. The speakers are from the US, Korea, and other countries.
教學目標Course Objectives
• 教授學生如何給一個生動及好的演講 • 概述髓母細胞瘤及其臨床上的進展及學習其他癌症的致病機轉 • 概述刺猬信號與AMPK在腦瘤發展中的所扮演的重要角色 • 增進研究學者的口語表達能力以促進其專業發展 • 概述如何準備優質的科學演講 • 讓學生熟悉不同的演講風格 • 增進學生公開演講經驗 • 促進學生間和自我評估技能的發展 • 提高學生批判思考的能力 • How to prepare an abstract • How to give a killer presentation •. To provide an overview of medulloblastoma and its clinical progress • To provide an overview of the important role of hedgehog signaling and AMPK in the growth of brain tumors • To promote the development of oral skills critical to the professional development of research scientists • To provide an overview of how to prepare an effective scientific presentation • To become familiar with different oral presentations styles • To provide an opportunity for students to gain experience in public speaking • To foster the development of peer- and self-assessment skills • To promote the ability to think critically
先修科目Prerequisites
None
教學方式Teaching Methods
線上教學(如磨課師、翻轉教學) Online teaching, e.g., MOOCs, Flipped classroom, SPOCs 講課 Lecturing 學生實作 Student hands-on practice 一分鐘回饋、其他 One-minute feedback, Others 學生上台報告、角色演練 Oral presentation, Role playing
評量方式Assessment
實作測驗 Practical exam 個人上台報告 Oral Report 出席狀況 Class attendance
參考書目Reference
1. Book title: Neurooncology (ISBN 978-953-51-4781-7); Chapter title: Medulloblastoma: Clinical Challenges and Emerging Molecular Discoveries. 2016; Authors: Eric Q. Trieu, Sherri Y. Huang, Jer-Yen Yang* 2. eBook title: Recent Advances in Brain Tumor (Open access ebook, Avid Science Publications) Chapter title: Targeting Medulloblastoma: Genetic and Metabolic Signatures in the Focus. 2016; Authors: Rui Zhang, Sherri Y. Huang, Jer-Yen Yang* 3. Book title: Handbook of Brain Tumor Chemotherapy. Chapter title: Targeting the sonic hedgehog pathway in brain cancers: Advances, limitations and future directions. 2018; Authors: Sherri Y. Huang, Jer-Yen Yang*
教學進度Course Schedule
2022/09/13 課堂簡介、師資說明及自我介紹 Introduction 楊哲彥(Yang, Jer-Yen)
2022/09/20 如何給一個精彩的演講:從你的肢體語言到幻燈片的內容準備 How to deliver a stunning scientific presentation: From your body language to a slide presentation 楊哲彥(Yang, Jer-Yen)
2022/09/27 髓母細胞瘤簡介及臨床上的問題 1 Overview: Introduction of Medulloblastoma, Clinical Obstacle in Medulloblastoma 1 楊哲彥(Yang, Jer-Yen)
2022/10/04 髓母細胞瘤簡介及臨床上的問題 2 Overview: Introduction of Medulloblastoma, Clinical Obstacle in Medulloblastoma 2 楊哲彥(Yang, Jer-Yen)
2022/10/11 學生報告五分鐘演說 5 mins talk (3-4 students) + video record 楊哲彥(Yang, Jer-Yen)
2022/10/18 從學生報告的影片來討論其表現 Presentation review and evaluation 楊哲彥(Yang, Jer-Yen)
2022/10/25 探討內緣性傳導蛋白變異在先天性心脏病 Mutations in Endocytic traffic proteins and congenital heart defects 楊哲彥(Yang, Jer-Yen)
2022/11/01 蛋白質及分子結構模擬分析 1 Protein docking 1 楊哲彥(Yang, Jer-Yen)
2022/11/08 期中報告 Mid-term EXAM 楊哲彥(Yang, Jer-Yen)
2022/11/15 蛋白質及分子結構模擬分析 2 Protein docking 2 楊哲彥(Yang, Jer-Yen)
2022/11/22 利用分子分析在乳癌病患之個人化療法 Molecular characterization of breast cancer for personalized therapy 楊哲彥(Yang, Jer-Yen) 山口浩史(Yamaguchi Hirohito)
2022/11/29 非酒精性肝炎之最新探討及經驗分享 NASH and biotech/ pharma experience 楊哲彥(Yang, Jer-Yen)
2022/12/06 模式動物在生物醫學上之應用 Mouse genetics and it’s application in biomedical research 楊哲彥(Yang, Jer-Yen)
2022/12/13 學生報告 1 Student presentation 1 楊哲彥(Yang, Jer-Yen)
2022/12/20 學生報告 2 Student presentation 2 楊哲彥(Yang, Jer-Yen)
2022/12/27 從學生報告的影片來討論其表現 Presentation review, discussion, and evaluation 楊哲彥(Yang, Jer-Yen)
2023/01/03 整體總評估, 期末總結與檢討 Overall evaluation 楊哲彥(Yang, Jer-Yen)
2023/01/10 期末考 Final exam 楊哲彥(Yang, Jer-Yen)