使選修本課程學生初步瞭解動物複製、胚幹細胞與其它多能性幹細胞之生物學特性。期能培養具備從事農業科技、生醫研究與再生醫學專業初階學能之人才,並使瞭解如何改善以動物複製與胚幹細胞技術為手段之生殖效率以及學習設計解決相關問題之方案。
Elective This course enables students to a preliminary understanding of animal reproduction, the biological characteristics of embryonic stem cells and other pluripotent stem cells
先修科目Prerequisites
教學方式Teaching Methods
評量方式Assessment
期末報告 、專題報告 、出席狀況 、課堂參與與表現
參考書目Reference
教學進度Course Schedule
2022/02/21 動物複製與胚幹細胞之歷史與演進
(Historical development in animal cloning and ES cell technology)
朱志成(Jyh-Cherng Ju) 2022/02/28 哺乳動物複製之基礎理論
(Principles of mammalian cloning)
朱志成(Jyh-Cherng Ju) 2022/03/07 卵子與胚之成熟、受精與其後續發育
(Maturation, fertilization and development of oocytes and embryos)
朱志成(Jyh-Cherng Ju) 2022/03/14 哺乳動物卵子激活與發育在分子生物與細胞學方面之機轉
(Mechanisms in oocyte activation and development)
朱志成(Jyh-Cherng Ju) 2022/03/21 細胞週期之調控原理
(Principles in regulation of cell cycle)
朱志成(Jyh-Cherng Ju) 2022/03/28 核轉置與重組胚之激活方法
(Methodologies of nuclear transfer and cellular reprogramming)
朱志成(Jyh-Cherng Ju) 2022/04/04 供、受核細胞基因之甲基化與重整合之機制
(Methylation and reprogramming of recipient ooplasm and donor cells)
朱志成(Jyh-Cherng Ju) 2022/04/11 早期胚胎與複製胚發育之基因表現與其訊息傳導
(Gene expression and signaling of cloned embryos)
朱志成(Jyh-Cherng Ju) 2022/04/18 邀請專家專題
Invited lecture
朱志成(Jyh-Cherng Ju) 2022/04/25 始基生殖細胞、胚幹細胞與飼養層細胞之體外培養
(Culture of primordial germ cells, embryonic stem cells and feeders)
朱志成(Jyh-Cherng Ju) 2022/05/02 利用複製技術產製基因轉殖動物與再複製
(Cloning/re-cloning of cloned and transgenic animals)
朱志成(Jyh-Cherng Ju) 2022/05/09 源自複製胚胚幹細胞之體外培養與供核細胞株之製備
(Culture of donor cells cloned embryo-derived embryonic stem cells)
朱志成(Jyh-Cherng Ju) 2022/05/16 利用複製技術產製胚幹細胞
(Isolation of embryonic stem cells using cloning technology)
朱志成(Jyh-Cherng Ju) 2022/05/23 誘導性多能幹細胞之產製與培養
(Induction and culture of induced pluripotent stem cells)
朱志成(Jyh-Cherng Ju) 2022/05/30 源自精卵異常不孕症治療之多元化
(Treatments of infertility caused by abnormal eggs and sperm)
朱志成(Jyh-Cherng Ju) 2022/06/06 動物複製與多能性幹細胞在臨床醫學之應用
(Clinical implications in animal cloning and pluripotent stem cells)
朱志成(Jyh-Cherng Ju) 2022/06/13 複製、老化與倫理議題
(Cloning, aging and ethical issues)
朱志成(Jyh-Cherng Ju) 2022/06/20 學生個別簡報
Discussion, presentation
朱志成(Jyh-Cherng Ju)