課程內容包括機率法則與機率於醫學之應用、機率之理論分布、統計理論之抽樣分布、假設檢定與信賴區間，統計方法之配對t檢定與Student’s t檢定、變異數分析、無母數統計分析方法中之訊號測驗法(The sign test)、魏克森訊號等級測驗法(Wilcoxon signed rank test)和魏克森等級和測驗法(Wilcoxon rank sum test)、卡方檢定、McNemar’s檢定、Mantel-Haenszel方法、Pearson與Spearman相關、複迴歸模式與羅吉斯模式。
教學目標Course Objectives
介紹常用之醫學統計分析方法之原理與應用，以增進學生對生物統計方法之認識與應用。
The objective of this course is to provide an introduction to the study of biostatistics. It provides comprehensive coverage of the major components involved in dealing with collections of numbers and ways in which to summarize, explore, and explain them, probability, sampling, methods of statistical inference and biostatistical concepts that are applied in public health and clinical research.
先修科目Prerequisites
無
Nil
教學方式Teaching Methods
講課
Lecturing
e化教學
e-teaching
評量方式Assessment
隨堂筆試測驗
In-class exam
期末筆試
Final exam
出席狀況
Class attendance
課堂參與與表現
Class involvement
十次的平時考與期末考。
參考書目Reference
Principles of Biostatistics, Marcello Pagano & Kimberlee Gauvreau, Duxbury, 2000.
教學進度Course Schedule
2016/09/23 課程介紹
Introduction to the Course
李采娟(Tsai-Chung Li) 2016/09/30 生物統計原理：數值摘要測量
Principles of Biostatistics: Numerical Summary Measures
李采娟(Tsai-Chung Li) 2016/10/07 生物統計原理：機率
Principles of Biostatistics: Probability
李采娟(Tsai-Chung Li) 2016/10/14 生物統計原理：二項式分布與卜瓦松分布
Principles of Biostatistics: Binomial Distribution & Poisson Distribution
李采娟(Tsai-Chung Li) 2016/10/21 生物統計原理：常態分布
Principles of Biostatistics: Normal Distribution
李采娟(Tsai-Chung Li) 2016/10/28 生物統計原理：平均數的抽樣分布
Principles of Biostatistics: Sampling Distribution of the Mean
李采娟(Tsai-Chung Li) 2016/11/04 生物統計原理：信賴區間
Principles of Biostatistics: Confidence Intervals
李采娟(Tsai-Chung Li) 2016/11/11 期中考試
Mid-term examination
李采娟(Tsai-Chung Li) 2016/11/18 生物統計原理：假設檢定
Principles of Biostatistics: Hypothesis Testing
李采娟(Tsai-Chung Li) 2016/11/25 生物統計原理：兩組平均值的比較
Principles of Biostatistics: Comparison of Two Means
李采娟(Tsai-Chung Li) 2016/12/02 生物統計原理：無母數統計方法
Principles of Biostatistics: Nonparametric Methods
李采娟(Tsai-Chung Li) 2016/12/09 生物統計原理：變異數分析
Principles of Biostatistics: Analysis of Variance
李采娟(Tsai-Chung Li) 2016/12/16 生物統計原理：列聯表
Principles of Biostatistics: Contingency Table
李采娟(Tsai-Chung Li) 2016/12/23 生物統計原理：多重2 x2列聯表
Principles of Biostatistics: Multiple 2x2 Contingency Tables
李采娟(Tsai-Chung Li) 2016/12/30 生物統計原理：相關係數
Principles of Biostatistics: Correlation
李采娟(Tsai-Chung Li) 2017/01/06 生物統計原理：簡單線性迴歸
Principles of Biostatistics: Simple Linear Regression
李采娟(Tsai-Chung Li) 2017/01/13 期末考試
Final examination
李采娟(Tsai-Chung Li)