藥理學課程是使大學生生對藥理原理以及使用和應用這些信息的能力有深入的了解。包括的主題:藥物發現,藥效學,藥代動力學和藥物基因組學的基本原理;自主神經作用藥;心血管與腎藥物;對平滑肌具有重要作用的藥物;中樞神經系統藥物;用於治療發炎症,痛風和血液疾病的藥物;內分泌藥物 化療藥物;毒理學; 和特殊主題。此序列在已被吸收的信息的基礎上構建新信息。例如,自主神經系統藥理學的早期介紹使學生能夠將在其他地方學到的生理學和神經科學與他們正在學習的藥理學相結合,並為他們準備了解其他藥物影響的自主神經作用。這對於心血管用藥和中樞神經系統藥物尤其重要。並將通過教學講座介紹每個主題並提供必要的信息;隨後的會議將重點討論此信息的使用和應用。這些會議將使用問題導向學習、討論課、及案例討論方法討論課文內容或研究問題,並由教師擔任討論促進者。
The goal of Phamcology course is to provide under-graduate students with an in-depth understanding of pharmacological principles as well as the ability to use and apply this information. Topics to be included: basic principles of drug discovery, pharmacodynamics, pharmacokinetics, and pharmacogenomics; autonomic drugs; cardiovascular-renal drugs; drugs with important actions on smooth muscle; central nervous system drugs; drugs used to treat inflammation, gout, and diseases of the blood; endocrine drugs; chemotherapeutic drugs; toxicology; and special topics. This sequence builds new information on a foundation of information already assimilated. For example, early presentation of autonomic nervous system pharmacology allows students to integrate the physiology and neuroscience they have learned elsewhere with the pharmacology they are learning and prepares them to understand the autonomic effects of other drugs. This is especially important for the cardiovascular and central nervous system drug groups. These sessions will involve a discussion of research papers or research problems using the Problem-Basic-Learning (PBL), Lecture, and Case study with the faculty acting as discussion facilitators. For the more quantitative aspects of this course, quantitative problem-solving will also be used.
教學目標Course Objectives
藥理學之教學目標,在於養成中醫學生六大稱職能力,教導學生認識藥物之作用原理及相關知識,並著重應用與疾病治療之關係
Base on six general competencies, to teach the Chinese medical students with general understanding of how drugs work and
how their actions may be modified with the perspectives from their clinical applications
先修科目Prerequisites
解剖、生理、生化、微免等
Anatomy, physiology, biochemistry and microbiology & immunology
教學方式Teaching Methods
非同步教學(主要提供線上影音教材,透過線上教學平台進行作業及討論)
Asynchronous Online Learning
講課
Lecturing
習題練習、書面報告
Exercise, Written report
評量方式Assessment
期中筆試
Midterm exam
隨堂筆試測驗
In-class exam
期末筆試
Final exam
前後測比較進步與成長
Progress evaluation
出席狀況
Class attendance
課堂參與與表現
Class involvement
期中筆試(Midterm exam)
隨堂筆試測驗(In-class exam)
期末筆試(Final exam)
出席狀況(Class attendance)
課堂參與與表現(Class involvement)
參考書目Reference
1.*書 名:Lippincott’s Illustrated Reviews Pharmacology 6th (2016)
作 者: Howland. 出版社:Lippincott
2. 書 名:Basic & Clinical Pharmacology, 14th(2017)作 者: B. G. Katzung. 出版社:McGraw-Hill
http://accessmedicine.mhmedical.com/book.aspx?bookID=1193
3. 書 名:Katzung & Trevor's Pharmacology: Examination & Board Review, 11e
http://accessmedicine.mhmedical.com/book.aspx?bookID=1568
4. 書 名:Goodman & Gilman’s The Pharmacological Basis of Therapeutics 13th ed. (2016)
http://accessmedicine.mhmedical.com/book.aspx?bookID=1613
教學進度Course Schedule
2021/03/03 ‧ 第1章. 藥理學簡介
‧ 第2章. 藥物受體和藥效學
1. Basic principles of Pharmacology
2. Drug receptors & Pharmacodynamics
陳玉芳(Yuh-Fung Chen) 2021/03/10 ‧ 第3章. 藥品動力學和藥效學: 合理劑量 & 藥物作用的時程
‧ 第4章. 藥物生體轉化
1. Pharmacokinetics & Pharmacodynamics
2. Drug Biotransformation
陳玉芳(Yuh-Fung Chen) 2021/03/17 第5章. 藥物的開發和管制
Development & Regulation of Drugs
陳玉芳(Yuh-Fung Chen) 2021/03/24 第6章. 自主神經藥理學簡介
第27章. 骨骼肌鬆弛劑
Introduction to Autonomic Pharmacology
楊春茂(Yang, Chuen-Mao) 2021/03/31 ‧第7章. 膽鹼受體作用和膽鹼酯酶抑制藥
‧ 第8章. 膽鹼受體阻斷藥
1. Cholinoceptor-Activating and Cholinesterase-Inhibiting drugs
2. Cholinoceptor-Blocking Drugs
楊春茂(Yang, Chuen-Mao) 2021/04/07 ‧ 第9章. 腎上腺素受體與交感神經作用藥
‧ 第10章. 腎上腺素受體拮抗劑藥
1. Adrenoceptor-Activating and Other sympathomimetic Drugs
2. Adrenoceptor Antagonist Drugs
楊春茂(Yang, Chuen-Mao) 2021/04/14 第29章. 呼吸道用藥
1. Drugs used in Rrespiratory
2. Skeletal Muscle Relaxants
謝文聰(Hsieh Wen-Tsong) 2021/04/21 4/21(三)第九節 期 中 測 驗
4/21 17:05-17:55 MId-term exam
陳玉芳(Yuh-Fung Chen)謝文聰(Hsieh Wen-Tsong)楊春茂(Yang, Chuen-Mao) 2021/04/28 第31章. 胃腸道用藥
Drugs used in the Treatment of G-I Diseases
謝文聰(Hsieh Wen-Tsong) 2021/05/05 ‧ 第21章. 中樞神經藥理學簡介
‧ 第22章. 鎮靜安眠藥物
1. Introduction to the Pharmacology of CNS drugs
2. Sedative-Hypnotic drugs
譚思濰(Tan Tzu-Wei) 2021/05/12 ‧ 第23章. 酒
‧ 第24章. 抗癲癇藥物
1. The Alcohols
2. Antiseizure Drugs
譚思濰(Tan Tzu-Wei) 2021/05/19 ‧ 第28章. 帕金森病和其他用藥
Pharmacologic Management of Parkinsonism
盧大宇(Dah-Yuu Lu) 2021/05/26 ‧ 第25章. 全身麻醉劑
‧ 第26章. 局部麻醉劑
1. General Anesthetics
2. Local Anesthetics
湯智昕(Tang Chih-Hsin) 2021/06/02 第29章. 抗精神病藥與鋰劑
第30章. 抗抑鬱藥物
1. Antipsychotic Agents and Lithium
2. Antidepressant Agents
湯智昕(Tang Chih-Hsin) 2021/06/09 ‧ 第31章. 阿片類藥物鎮痛藥和拮抗劑
Opioid Analgesics and Antagonists
湯智昕(Tang Chih-Hsin) 2021/06/16 ‧ 第32章. 藥物濫用
. 第44章 毒理學
Drugs of Abuse
Toxicology
湯智昕(Tang Chih-Hsin) 2021/06/23 6/23 (三)第九節 期末考試
Final exam 6/19 17:05-17:55
譚思濰(Tan Tzu-Wei)謝文聰(Hsieh Wen-Tsong)湯智昕(Tang Chih-Hsin)盧大宇(Dah-Yuu Lu) 2021/06/30 課後複習
‧ 第56章. 毒理學理學: 職業與環境毒物學
‧ 第57章. 重金屬中毒和螯合劑
Section IX. Toxicology
• Chapter 56. Toxicology: Occupational & Environmental
• Chapter 57. Heavy Metal Intoxication & Chelators
• Chapter 58. Management of the Poisoned Patient
湯智昕(Tang Chih-Hsin)