要求學生充分熟悉：生物分子之種類，物理化學性質及其生物功能﹔新陳代謝及其調解﹔生命之分子基礎及其調控。
期望學生能以正常之生化生理功能為主軸，推論病變的原因及可能的治療。
引發學生對生命科學研究的興趣，學以致用於個人保健及日常生活
Biochemistry is essential to the study and practice of medicine. The intention of the course is for students to
(1) know the composition, structure, and function of the major classes of biological molecules.
(2) understand the biochemical principles, including: structure-function correlation; chemical reactivity, kinetics and equilibrium; thermodynamics, membrane structure and function; metabolic energy pathways, integration and regulation.
(3) understand how improper regulation of these biochemical processes can lead to human disease.
先修科目Prerequisites
生物學、普通化學、有機化學
Biology, General Chemistry, Organic Chemistry
教學方式Teaching Methods
評量方式Assessment
三次段落成績平均並加計PBL成績，段落成績包含段考及平時成績(小考、出席、作業等)。
參考書目Reference
教科書
Textbook of Biochemistry with Clinical Correlations, 7th ed. (2011), Thomas M. Devlin
參考書
1. Lehninger Principles of Biochemistry,6th ed. (2013) D. L. Nelson and M. M. Cox
2. Harper’s Illustrated Biochemistry, 29th ed. (2012), Robert K. Murray. et al.
3. Biochemistry, 7th ed. (2012) Jeremy M. Berg. John L. Tymoczko, Lubert Stryer
4. Lippincott’s Illustrated Reviews: Biochemistry, 5th ed. (2011), Pamela C. Champe, et al
教學進度Course Schedule
2013/09/13 Eukaryotic Cell Structure
Eukaryotic Cell Structure
林錦芬 2013/09/14 Protein I: Composition and Structure
Protein I: Composition and Structure
林錦芬 2013/09/27 Protein I: Composition and Structure
Protein I: Composition and Structure
林錦芬 2013/10/04 Protein II: Structure-Function Relationships in Protein Families
Protein II: Structure-Function Relationships in Protein Families
林錦芬 2013/10/11 Protein II: Structure-Function Relationships in Protein Families
Protein II: Structure-Function Relationships in Protein Families
林錦芬 2013/10/18 Enzymes: Classification, Kinetics, and Control
Enzymes: Classification, Kinetics, and Control
林麗娟(Li-Jen Lin) 2013/10/23 第一次段考12:10~13:00， chapter 1, 3, 9
The First Examination:12:10~13:00， chapter 1, 3, 9
林錦芬 2013/10/25 Enzymes: Classification, Kinetics, and Control
Enzymes: Classification, Kinetics, and Control
林麗娟(Li-Jen Lin) 2013/11/01 Enzymes: Classification, Kinetics, and Control
Enzymes: Classification, Kinetics, and Control
林麗娟(Li-Jen Lin) 2013/11/08 Micronutrients: Vitamins and Minerals
Micronutrients: Vitamins and Minerals
呂郁蕙(Liu, Yu-Huei) 2013/11/15 Bioenergetics and Oxidative Metabolism
Bioenergetics and Oxidative Metabolism
呂郁蕙(Liu, Yu-Huei) 2013/11/22 Bioenergetics and Oxidative Metabolism
Bioenergetics and Oxidative Metabolism
呂郁蕙(Liu, Yu-Huei) 2013/11/29 Carbohydrates Structure (page 1124)
Carbohydrates Structure (page 1124)
詹淑秦(Hsu Chin Chan) 2013/12/04 第二次段考12:10~13:00， chapter 10,14,26
Exam 2# 12:10~13:00， chapter 10,14,26
呂郁蕙(Liu, Yu-Huei)林麗娟(Li-Jen Lin) 2013/12/06 Carbohydrate Metabolism I: Major Metabolic Pathways
Carbohydrate Metabolism I: Major Metabolic Pathways
詹淑秦(Hsu Chin Chan) 2013/12/13 Carbohydrate Metabolism I: Major Metabolic Pathways
Carbohydrate Metabolism I: Major Metabolic Pathways
詹淑秦(Hsu Chin Chan) 2013/12/20 Case study
Case study
林清淵(Ching-Yuang Lin) 2013/12/27 Carbohydrate Metabolism II: Special Metabolic Pathways
Carbohydrate Metabolism II: Special Metabolic Pathways
詹淑秦(Hsu Chin Chan) 2014/01/03 Carbohydrate Metabolism II: Special Metabolic Pathways
Carbohydrate Metabolism II: Special Metabolic Pathways
詹淑秦(Hsu Chin Chan) 2014/01/08 第三次段考12:10~13:00， chapter 15,16 and page 1124-1128
Exam #3:12:10~13:00， chapter 15,16 and page 1124-1128
詹淑秦(Hsu Chin Chan)