Introduce the dermatological pharmacology, including topical application agents, the mechanisms and side effects of these agents.
教學目標Course Objectives
諸多藥物應用於治療皮膚方面疾病，包含疼痛、發炎、發癢、頭皮屑、禿頭掉髮等。而此些藥物之作用原理、機轉及副作用應深入瞭解，且皮膚為身體最大器官，亦可作為藥物或藥用化妝品吸收之路徑，而如何突破皮膚屏障於標靶器官達一定濃度，實為一重要之課題。本課程將延續上學期課程繼續介紹常使用於皮膚表面之藥物及其作用機轉與副作用等，如掉髮、肥胖、抗黴菌、抗癌及自主人經系統方面用藥。期望學生能明瞭此些藥物及其作用機轉，更期盼能將此些藥物安全而有效應用於美容保養領域。另將介紹關穿皮吸收之理論、應用及量測，以及促進穿皮吸收之方法。
Lots of medicine applied in treating skin disorder involving acne, inflammatory, and allergy. The principle, mechanism and side effects of these drugs should be understood. Skin is the biggest organ of the body and would be a good route for drug absorption. The first half of the curriculum will introduce the principles, methods and measurements of percutaneous absorption. The second half will introduce the mechanisms and side effects of the topical drugs including chemical therapy agents, antibiotics and alopecia agents. Students may understand the mechanisms of the drug and apply in cosmaceuticals efficiently and safely.
先修科目Prerequisites
教學方式Teaching Methods
講課
Lecturing
習題練習、書面報告
Exercise, Written report
一分鐘回饋、其他
One-minute feedback, Others
評量方式Assessment
期中筆試
Midterm exam
期末筆試
Final exam
出席狀況
Class attendance
課堂參與與表現
Class involvement
期中考40%、期末考40%、平時成績及報告20%
Middle-examination 40%, final-examination 40%, report 20%
參考書目Reference
1. Journal paper
2. Goodman and Gilman’s The Pharmacological Basis of Therapeutics 11/E McGRAW-HILL USA 2006.
3. Peter Elsner，ed. Cosmeceuticals Drug vs. Cosmetics. Marcel Dekker New York. USA.
4. Zoe Diana Draelos. ed. Cosmeceuticals. Elsevier Saunders, 2005
5. 張聰明著，美容藥物學，新文京出版社，台北，2007。