Introduction of dermatological pharmacology, topical drugs, the mechanisms and side effects of NSAIDs, steroids, anti-acne agents, antibiotics and antihistamine agent.
教學目標Course Objectives
諸多藥物應用於治療皮膚方面疾病，而其作用之原理、機轉及副作用應深入瞭解，且皮膚為身體最大器官，亦可作為藥物或藥用化妝品吸收之路徑，而如何突破皮膚屏障於標靶器官達一定濃度，實為一重要就課題。本課程前半部將介紹藥物經由皮膚吸收之原理、方式及評估之方法與原理。後半部將介紹常使用於皮膚表面之藥物及其作用機轉與副作用等，如非固醇類抗發炎藥、固醇類藥物、治療痤瘡及掉髮等類藥物。期望學生能明瞭此些藥物及其作用機轉，更期盼能將此些藥物安全而有效應用於美容保養領域。
Lots of medicine applied in treating skin disorder involving acne, inflammatory, and allergy. The principle, mechanism and side effects of these drugs should be understood. Skin is the biggest organ of the body and would be a good route for drug absorption. The first half of the curriculum will introduce the principles, methods and measurements of percutaneous absorption. The second half will introduce the mechanisms and side effects of the topical drugs including NSAIDs, steroids, anti-acne agents, antibiotics and alopecia agents. Students may understand the mechanisms of the drug and apply in cosmaceuticals efficiently and safely.
期中筆試
Midterm exam
期末筆試
Final exam
出席狀況
Class attendance
課堂參與與表現
Class involvement
期中考、期末考、平時成績
Middle-examination, final-examination, report
參考書目Reference
1. Peter Elsner，ed. Cosmeceuticals Drug vs. Cosmetics. Marcel Dekker New York. USA.
2. Zoe Diana Draelos. ed. Cosmeceuticals. Elsevier Saunders, 2005
3. Goodman and Gilman’s The Pharmacological Basis of Therapeutics 11/E McGRAW-HILL USA 2006.
4. 張聰明著，美容藥物學，新文京出版社，台北，2007。
5. Neal. Glance of Pharmacology. 2013.
6. Pocket of Pharmacology. 2011.
教學進度Course Schedule
2023/09/15 皮膚藥理學簡介
Introduction of dermatological pharmacology
江秀梅(Hsiu-Mei Chiang) 2023/09/22 皮膚藥物動力學
Pharmacokinetics
江秀梅(Hsiu-Mei Chiang) 2023/09/29 中秋節
Holiday
江秀梅(Hsiu-Mei Chiang) 2023/10/06 接受器與藥效學
Drug receptors & pharmacodynamic
江秀梅(Hsiu-Mei Chiang) 2023/10/13 藥物動力學 吸收分布排除
Pharmacokinetics(absorption, distribution and excretion)
江秀梅(Hsiu-Mei Chiang) 2023/10/20 生物轉換/代謝
Drug biotransformation/ metabolism
江秀梅(Hsiu-Mei Chiang) 2023/10/27 鎮痛解熱劑
Analgesic, Antipyretic Agents
江秀梅(Hsiu-Mei Chiang) 2023/11/03 鴉片類鎮痛劑
Opioid analgesics
江秀梅(Hsiu-Mei Chiang) 2023/11/10 期中考
Mid-term
江秀梅(Hsiu-Mei Chiang) 2023/11/17 局部麻醉劑
Local anaesthetcs
楊麗嬋(Li-Chan Yang) 2023/11/24 磺胺藥及抗生素I
Sulfa drugs and Antibiotics I
楊麗嬋(Li-Chan Yang) 2023/12/01 2023/12/01皮膚藥理學暫停-因應2023台灣國際創新生物醫學峰會活動。12/1星期五將舉行台灣國際創新生物醫學峰會，此次會議邀請來自各國無數國際知名演講者，包括美國國家科學院院士、中央研究院院士以及國內外優秀學者等，提供同學吸收國際新知識的盛會，歡迎同學踴躍參加。
抗生素 II
The 2023 Taiwan International Innovative Biomedical Summit will be held on Friday 12/1, featuring numerous internationally renowned speakers from various countries, including members of the National Academy of Sciences in the United States, Academicians of the Academia Sinica, and outstanding scholars. This conference offers students the opportunity to absorb new international knowledge. We warmly welcome students to actively participate
Antibiotics II
楊麗嬋(Li-Chan Yang) 2023/12/08 抗生素 III
Antibiotics III
楊麗嬋(Li-Chan Yang) 2023/12/15 抗黴菌劑 I
Antifungus agents I
楊麗嬋(Li-Chan Yang) 2023/12/22 抗黴菌劑 II
Antifungus agents II
楊麗嬋(Li-Chan Yang) 2023/12/29 抗病毒藥 I
Antivirus agents I
楊麗嬋(Li-Chan Yang) 2024/01/05 抗病毒藥 II
Antivirus agents II
楊麗嬋(Li-Chan Yang) 2024/01/12 期末考
Final term
楊麗嬋(Li-Chan Yang)