課程概述 (Course Description)：1. 有機鹵化物，2. 醇、酚、硫醇、醚與硫化物，3. 酫類及酮類：親核性加成反應，4. 羧酸類及腈類，5. 羧酸類衍生物：親核性醯基取代反應，6. 羰基阿法-取代反應，羰基縮合反應，7. 胺類及雜環化合物。(1.Organolides; 2. Alcohol, phenol, and Thiols; Ethers and sulfides; 3. Aldehydes and ketones; 4. carboxylic acids and nitriles; 5. Carboxylic acid derivatives; 6. Carbonyl Alpha substitution and condensation reactions; amines and heterocycles)
教學目標Course Objectives
在本課程中，我們著重於有機化合物的反應性、反應機構與逆合成分析的探討。本課程學習目標旨在幫助學生學會如何解決生活中實際發生的有機化學問題。
We will emphasize the reactivity of organic compounds, mechanisms, and retrosynthetic analysis in this course. The goal of the course is to help students learn how to solve practical problems in organic chemistry in our life.
期中筆試
Midterm exam
期末筆試
Final exam
出席狀況
Class attendance
課堂參與與表現
Class involvement
其它
Others
期中及學期考試成績占90%為主，平時問題討論表現及上課出席紀錄占10%。(The total mark of this subject accounts for 90% with the achievement of the Mid and Final exam is as the main fact, and the expression of question discussion at ordinary times and the attendance account for 10%.)
參考書目Reference
1. John McMurry: Organic Chemistry, 9th ed. 2015 (授課教科書，teaching textbook).
2. John E. McMurry: Organic Chemistry, 8th ed. 2012.
3. Atkins, Carey, and Ong: Organic Chemistry: A Brief Course, 3rd ed. 2013.
4. Organic Chemistry: With Biological Applications; John McMurry (2nd ed. 2011).
5. John McMurry: Fundamental of Organic Chemistry, 7th ed. 2011.
6. Ghatak (Arthur): A Textbook of Organic Chemistry and Problem Analysis (2014).
7. Ray (Author): Reaction Mechanisms in Organic Chemistry (2013).
8. Dubey (Author): A Text Book of Organic Chemistry (2013).
9. Paul Y. Bruice: Essential Organic Chemistry, 3rd ed. 2016.
教學進度Course Schedule
2019/07/01 課程簡介/有機鹵化物/醇類及酚類
Introduction/Organohalides/Alcohols and Phenols
吳錦生(Wu, Chin-Sheng) 2019/07/02 醇類及酚類/醚類及環氧化物；硫醇類及硫化物
Alcohols and Phenols/Ethers and Epoxides; Thiols and Sulfides
吳錦生(Wu, Chin-Sheng) 2019/07/03 酫類及酮類：親核性加成反應/羧酸類及腈類
Aldehydes and Ketones: Nucleophilic Addition Reactions/Carboxylic Acids and Nitriles
吳錦生(Wu, Chin-Sheng) 2019/07/04 羧酸類及腈類/羧酸類衍生物：親核性醯基取代反應
Carboxylic Acids and Nitriles/Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reaction
吳錦生(Wu, Chin-Sheng) 2019/07/08 期中考試/羧酸類衍生物：親核性醯基取代反應
Mid exam/Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reaction
吳錦生(Wu, Chin-Sheng) 2019/07/09 羰基阿法-取代反應
Carbonyl Alpha-Substitution Reactions
吳錦生(Wu, Chin-Sheng) 2019/07/10 羰基縮合反應
Carbonyl Condensation Reactions
吳錦生(Wu, Chin-Sheng) 2019/07/11 羰基縮合反應/胺類及雜環化合物
Carbonyl Condensation Reaction/Amines and Heterocycles
吳錦生(Wu, Chin-Sheng) 2019/07/15 胺類及雜環化合物/學期考試
Amines and Heterocycles/Final exam
吳錦生(Wu, Chin-Sheng)